‘The next is nanopores, that's our oldest line of exploration and that has now resulted in DNA sequencers determined by nanopores. We pull specific DNA strands by way of a nanopore and may then study off the nucleotide sequence. Very lately, we even managed to read out a single protein for The very first time making use of this technique. But this line of research is not only about acquiring instruments, but in addition about serious biological concerns.
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‘It absolutely was basically a issue of choosing up a book on mobile biology and starting to read. I'd come from a world of extremely-large vacuums, cryostats and quantum phenomena, and now I was Doing the job at area temperature with molecular biology kits.
Considering that 2000, Dekker has shifted the main target of his get the job done towards biophysics in which he scientific tests the properties of single biomolecules and cells using the equipment of nanotechnology. This alteration of area was driven by his fascination for that extraordinary functioning of biological molecular constructions, and also via the long-term viewpoint a large number of appealing discoveries is usually expected Within this area.[5] Existing traces of exploration in his biophysics team are in the areas of:[6]
Dekker is naast zijn wetenschappelijk werk ook bekend vanwege zijn belangstelling voor de relatie tussen geloof en wetenschap en de discussie rond clever style and design in 2005. (nl)
Case in point (3) of bending configurations in 3D simulations of DNA rods on nanopores. A percentage of the membrane is demonstrated in grey, the rim of your pore is highlighted in crimson, along with a 3D rendering of your movement from the DNA rod is exhibited.
Duration Charge of specific carbon nanotubes by nanostructuring Along with the scanning tunneling microscope
He also uncovered time to write down various books, send out almost forty thousand tweets and direct A prosperous study team at Delft College of Engineering. ‘It doesn’t experience like perform’, he suggests. ‘I’m just terribly curious.’
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But carbon nanotubes have remained a investigation matter of significant curiosity to several. Certainly, the outlook cees dekker on employing carbon nanotubes to create sensible devices, in areas which include radio-frequency electronics, electronic electronics and flexible electronics, remains dazzling.
‘The concept that There may be this kind of thing as being a starting, a huge bang, is by now an interesting signpost to take into account that there was a creator. But additional frequently, and on The premise of pure rationality, I also arrive at a Christian interpretation of reality. An atheistic worldview is really a naturalistic worldview: fundamentally, you'll find only atoms and normal forces that we could evaluate.
1999, to start with measurement in the wavefunction of one molecular orbitals of carbon nanotubes; and discovery of kink heterojunctions of carbon nanotubes which gave decisive evidence for the new Luttinger description of interacting electrons in nanotubes
Electrical transport in monolayers of phthalocyanine molecular wires and AFM imaging of only one wire bridging two electrodes
Solid-point out nanopores have demonstrated to get a astonishingly flexible probe for single-molecule Assessment of DNA. I'll describe some of our the latest results – especially DNA knots – in addition to our efforts to develop the capabilities of strong-condition nanopores even additional, within the direction of one-protein detection, graphene nanopores, plasmonic nanopores, and DNA origami nanopores.